Amyloid Reduction by Amyloid-β Vaccination Also Reduces Mouse Tau Pathology and Protects from Neuron Loss in Two Mouse Models of Alzheimer's Disease

Shown to lower amyloid deposits and improve cognition in APP transgenic mouse models, immunotherapy appears to be a promising approach for the treatment of Alzheimer's disease (AD). Due to limitations in available animal models, however, it has been unclear whether targeting amyloid is sufficie...

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Detalhes bibliográficos
Main Authors: Wilcock, Donna M., Gharkholonarehe, Nastaran, Van Nostrand, William E., Davis, Judianne, Vitek, Michael P., Colton, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2871319/
https://ncbi.nlm.nih.gov/pubmed/19553436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1339-09.2009
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