Progression of Amyloid Pathology to Alzheimer's Disease Pathology in an Amyloid Precursor Protein Transgenic Mouse Model by Removal of Nitric Oxide Synthase 2

Alzheimer's disease (AD) is characterized by three primary pathologies in the brain: amyloid plaques, neurofibrillary tangles, and neuron loss. Mouse models have been useful for studying components of AD but are limited in their ability to fully recapitulate all pathologies. We crossed the APPS...

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Detalhes bibliográficos
Main Authors: Wilcock, Donna M., Lewis, Matthew R., Van Nostrand, William E., Davis, Judianne, Previti, Mary Lou, Gharkholonarehe, Nastaran, Vitek, Michael P., Colton, Carol A.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2621082/
https://ncbi.nlm.nih.gov/pubmed/18272675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5066-07.2008
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