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Experimental Investigation of Antibody-Mediated Clearance Mechanisms of Amyloid-β in CNS of Tg-SwDI Transgenic Mice

Novel amyloid precursor protein transgenic mice, which contain the Swedish as well as the vasculotropic Dutch and Iowa mutations (Tg-SwDI), were used to investigate the mechanisms of antibody-mediated clearance of amyloid-β (Aβ) from the brain. Export of the Aβ-DI peptide across the blood–brain barr...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Vasilevko, Vitaly, Xu, Feng, Previti, Mary Lou, Van Nostrand, William E., Cribbs, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673094/
https://ncbi.nlm.nih.gov/pubmed/18057195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2788-07.2007
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