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Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion

Mouse models have shown that cerebral hypoperfusion causes white matter disruption and memory impairment relevant to the study of vascular cognitive impairment and dementia. The associated mechanisms include inflammation and oxidative stress are proposed to drive disruption of myelinated axons withi...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Sigfridsson, Emma, Marangoni, Martina, Johnson, Jeffrey A., Hardingham, Giles E., Fowler, Jill H., Horsburgh, Karen
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6105641/
https://ncbi.nlm.nih.gov/pubmed/30135571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30675-4
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