Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system

The Uba6 (E1)-Use1 (E2) ubiquitin transfer cascade is a poorly understood alternative arm of the ubiquitin proteasome system (UPS) required for mouse embryonic development, independent of the canonical Uba1-E2-E3 pathway. Loss of neuronal Uba6 during embryonic development results in altered patterni...

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Main Authors: Lee, Peter C. W., Dodart, Jean-Cosme, Aron, Liviu, Finley, Lydia W., Bronson, Roderick T., Haigis, Marcia C., Yankner, Bruce A., Harper, J. Wade
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3640669/
https://ncbi.nlm.nih.gov/pubmed/23499007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.02.014
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