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UBA1: At the Crossroads of Ubiquitin Homeostasis and Neurodegeneration
Neurodegenerative diseases are a leading cause of disability and early death. A common feature of these conditions is disruption of protein homeostasis. Ubiquitin-like modifier activating enzyme 1 (UBA1), the E1 ubiquitin-activating enzyme, sits at the apex of the ubiquitin cascade and represents an...
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| Publicat a: | Trends Mol Med |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier Science Ltd
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4596250/ https://ncbi.nlm.nih.gov/pubmed/26432019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2015.08.003 |
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