Amyloid β-Protein Toxicity and the Pathogenesis of Alzheimer Disease

por Yankner, Bruce A., Lu, Tao
Publicado 2009

Inflammation links ageing to the brain

por Gabuzda, Dana, Yankner, Bruce A.
Publicado 2013

A γ-Secretase-independent Mechanism of Signal Transduction by the Amyloid Precursor Protein

por Hass, Matthew R., Yankner, Bruce A.
Publicado 2005

The Aging Stress Response

por Haigis, Marcia C., Yankner, Bruce A.
Publicado 2010

Neural mechanisms of ageing and cognitive decline

por Bishop, Nicholas A., Lu, Tao, Yankner, Bruce A.
Publicado 2010

Proteolytic release and nuclear translocation of Notch-1 are induced by presenilin-1 and impaired by pathogenic presenilin-1 mutations

por Song, Weihong, Nadeau, Philip, Yuan, Menglan, Yang, Xudong, Shen, Jie, Yankner, Bruce A.
Publicado 1999

β-Trcp couples β-catenin phosphorylation-degradation and regulates Xenopus axis formation

por Liu, Chunming, Kato, Yoichi, Zhang, Zhuohua, Do, Viet Minh, Yankner, Bruce A., He, Xi
Publicado 1999

Acceleration of Amyloid β-Peptide Aggregation by Physiological Concentrations of Calcium

por Isaacs, Adrian M., Senn, David B., Yuan, Menglan, Shine, James P., Yankner, Bruce A.
Publicado 2006

Neuronal Localization of Presenilin-1 and Association with Amyloid Plaques and Neurofibrillary Tangles in Alzheimer’s Disease

por Busciglio, Jorge, Hartmann, Henrike, Lorenzo, Alfredo, Wong, Caine, Baumann, Karlheinz, Sommer, Bernd, Staufenbiel, Matthias, Yankner, Bruce A.
Publicado en J Neurosci (1997)

Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system

por Lee, Peter C. W., Dodart, Jean-Cosme, Aron, Liviu, Finley, Lydia W., Bronson, Roderick T., Haigis, Marcia C., Yankner, Bruce A., Harper, J. Wade
Publicado 2013

Sustained axon regeneration induced by co-deletion of PTEN and SOCS3

por Sun, Fang, Park, Kevin K., Belin, Stephane, Wang, Dongqing, Lu, Tao, Chen, Gang, Zhang, Kang, Yeung, Cecil, Feng, Guoping, Yankner, Bruce A., He, Zhigang
Publicado 2011

The DNA damage response induces inflammation and senescence by inhibiting autophagy of GATA4

por Kang, Chanhee, Xu, Qikai, Martin, Timothy D., Li, Mamie Z., Demaria, Marco, Aron, Liviu, Lu, Tao, Yankner, Bruce A., Campisi, Judith, Elledge, Stephen J.
Publicado en Science (2015)

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

por Lipinski, Marta M., Zheng, Bin, Lu, Tao, Yan, Zhenyu, Py, Bénédicte F., Ng, Aylwin, Xavier, Ramnik J., Li, Cheng, Yankner, Bruce A., Scherzer, Clemens R., Yuan, Junying
Publicado 2010

Evolution of the Aging Brain Transcriptome and Synaptic Regulation

por Loerch, Patrick M., Lu, Tao, Dakin, Kelly A., Vann, James M., Isaacs, Adrian, Geula, Chengiz, Wang, Jianbin, Pan, Ying, Gabuzda, Dana H., Li, Cheng, Prolla, Tomas A., Yankner, Bruce A.
Publicado 2008

REST and Stress Resistance in Aging and Alzheimer’s Disease

por Lu, Tao, Aron, Liviu, Zullo, Joseph, Pan, Ying, Kim, Haeyoung, Chen, Yiwen, Yang, Tun-Hsiang, Kim, Hyun-Min, Drake, Derek, Liu, X. Shirley, Bennett, David A., Colaiácovo, Monica P., Yankner, Bruce A.
Publicado 2014

Regulation of Lifespan by Neural Excitation and REST

por Zullo, Joseph M., Drake, Derek, Aron, Liviu, O’Hern, Patrick, Dhamne, Sameer C., Davidsohn, Noah, Mao, Chai-An, Klein, William H., Rotenberg, Alexander, Bennett, David A., Church, George M., Colaiácovo, Monica P., Yankner, Bruce A.
Publicado en Nature (2019)

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

por Meyer, Katharina, Feldman, Heather M., Lu, Tao, Drake, Derek, Lim, Elaine T., Ling, King-Hwa, Bishop, Nicholas A., Pan, Ying, Seo, Jinsoo, Lin, Yuan-Ta, Su, Susan C., Church, George M., Tsai, Li-Huei, Yankner, Bruce A.
Publicado en Cell Rep (2019)

TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging

por Xu, Daichao, Jin, Taijie, Zhu, Hong, Chen, Hongbo, Ofengeim, Dimitry, Zou, Chengyu, Mifflin, Lauren, Pan, Lifeng, Amin, Palak, Li, Wanjin, Shan, Bing, Naito, Masanori Gomi, Meng, Huyan, Li, Ying, Pan, Heling, Aron, Liviu, Adiconis, Xian, Levin, Joshua Z., Yankner, Bruce A, Yuan, Junying
Publicado en Cell (2018)

DNA damage-induced alterations in chromatin contribute to genomic integrity and age-related changes in gene expression

por Oberdoerffer, Philipp, Michan, Shaday, McVay, Michael, Mostoslavsky, Raul, Vann, James, Park, Sang-Kyu, Hartlerode, Andrea, Stegmuller, Judith, Hafner, Angela, Loerch, Patrick, Wright, Sarah M., Mills, Kevin D., Bonni, Azad, Yankner, Bruce A., Scully, Ralph, Prolla, Tomas A., Alt, Frederick W., Sinclair, David A.
Publicado 2008

Synaptic NMDA receptor activity boosts intrinsic antioxidant defences

por Papadia, Sofia, Soriano, Francesc X., Léveillé, Frédéric, Martel, Marc-Andre, Dakin, Kelly A., Hansen, Henrik H., Kaindl, Angela, Sifringer, Marco, Fowler, Jill, Stefovska, Vanya, Mckenzie, Grahame, Craigon, Marie, Corriveau, Roderick, Ghazal, Peter, Horsburgh, Karen, Yankner, Bruce A., Wyllie, David J. A., Ikonomidou, Chrysanthy, Hardingham, Giles E.
Publicado 2008