Unclassified cardiomyopathy in a geriatric cat

Por Wolfson, Rachel
Publicado em 2005

The dawn of the age of amino acid sensors for the mTORC1 pathway

Por Wolfson, Rachel L., Sabatini, David M.
Publicado no Cell Metab (2017)

Nutrient Sensing Mechanisms Across Evolution

Por Chantranupong, Lynne, Wolfson, Rachel L., Sabatini, David M.
Publicado no Cell (2015)

HMGB1 induces human lung endothelial cell cytoskeletal rearrangement and barrier disruption

Por Wolfson, Rachel K., Chiang, Eddie T., Garcia, Joe G.N.
Publicado em 2010

Excessive Mechanical Stress Increases HMGB1 Expression in Human Lung Microvascular Endothelial Cells Via STAT3

Por Wolfson, Rachel K., Mapes, Brandon, Garcia, Joe G.N.
Publicado no Microvasc Res (2013)

Clinical Impact of Tumor Mutational Burden in Neuroblastoma

Por Hwang, William L, Wolfson, Rachel L, Niemierko, Andrzej, Marcus, Karen J, DuBois, Steven G, Haas-Kogan, Daphne
Publicado no J Natl Cancer Inst (2018)

Sestrin2 is a leucine sensor for the mTORC1 pathway

Por Wolfson, Rachel L., Chantranupong, Lynne, Saxton, Robert A., Shen, Kuang, Scaria, Sonia M., Cantor, Jason R., Sabatini, David M.
Publicado no Science (2015)

Rag GTPase-mediated regulation of mTORC1 by nutrients is necessary for neonatal autophagy and survival

Por Efeyan, Alejo, Zoncu, Roberto, Chang, Steven, Gumper, Iwona, Snitkin, Harriet, Wolfson, Rachel L., Kirak, Oktay, Sabatini, David D., Sabatini, David M.
Publicado em 2012

Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

Por Saxton, Robert A., Knockenhauer, Kevin E., Wolfson, Rachel L., Chantranupong, Lynne, Pacold, Michael E., Wang, Tim, Schwartz, Thomas U., Sabatini, David M.
Publicado no Science (2015)

mTORC1 activator SLC38A9 is required to efflux essential amino acids from lysosomes and use protein as a nutrient

Por Wyant, Gregory A., Abu-Remaileh, Monther, Wolfson, Rachel L., Chen, Walter W., Freinkman, Elizaveta, Danai, Laura V., Vander Heiden, Matthew G., Sabatini, David M.
Publicado no Cell (2017)

A Mouse Model of DEPDC5-related Epilepsy: Neuronal Loss of Depdc5 Causes Dysplastic and Ectopic Neurons, Increased mTOR Signaling, and Seizure Susceptibility

Por Yuskaitis, Christopher J., Jones, Brandon M., Wolfson, Rachel L., Super, Chloe E., Dhamne, Sameer C., Rotenberg, Alexander, Sabatini, David M., Sahin, Mustafa, Poduri, Annapurna
Publicado no Neurobiol Dis (2017)

The Sestrins interact with GATOR2 to negatively regulate the amino acid sensing pathway upstream of mTORC1

Por Chantranupong, Lynne, Wolfson, Rachel L., Orozco, Jose M., Saxton, Robert A., Scaria, Sonia M., Bar-Peled, Liron, Spooner, Eric, Isasa, Marta, Gygi, Steven P., Sabatini, David M.
Publicado no Cell Rep (2014)

KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1

Por Wolfson, Rachel L., Chantranupong, Lynne, Wyant, Gregory A., Gu, Xin, Orozco, Jose M., Shen, Kuang, Condon, Kendall J., Petri, Sabrina, Kedir, Jibril, Scaria, Sonia M., Abu-Remaileh, Monther, Frankel, Wayne N., Sabatini, David M.
Publicado no Nature (2017)

Parallel ascending spinal pathways for affective touch and pain

Por Choi, Seungwon, Hachisuka, Junichi, Brett, Matthew A., Magee, Alexandra, Omori, Yu, Iqbal, Noor-ul-Aine, Zhang, Dawei, DeLisle, Michelle M., Wolfson, Rachel L., Bai, Ling, Santiago, Celine, Gong, Shiaoching, Goulding, Martyn, Heintz, Nathaniel, Koerber, H. Richard, Ross, Sarah E., Ginty, David D.
Publicado no Nature (2020)

The amino acid transporter SLC38A9 is a key component of a lysosomal membrane complex that signals arginine sufficiency to mTORC1

Por Wang, Shuyu, Tsun, Zhi-Yang, Wolfson, Rachel, Shen, Kuang, Wyant, Gregory A., Plovanich, Molly E., Yuan, Elizabeth D., Jones, Tony D., Chantranupong, Lynne, Comb, William, Wang, Tim, Bar-Peled, Liron, Zoncu, Roberto, Straub, Christoph, Kim, Choah, Park, Jiwon, Sabatini, Bernardo L., Sabatini, David M.
Publicado no Science (2015)

Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma

Por Okosun, Jessica, Wolfson, Rachel L., Wang, Jun, Araf, Shamzah, Wilkins, Lucy, Castellano, Brian M., Escudero-Ibarz, Leire, Al Seraihi, Ahad Fahad, Richter, Julia, Bernhart, Stephan H., Efeyan, Alejo, Iqbal, Sameena, Matthews, Janet, Clear, Andrew, Guerra-Assunção, José Afonso, Bödör, Csaba, Quentmeier, Hilmar, Mansbridge, Christopher, Johnson, Peter, Davies, Andrew, Strefford, Jonathan C., Packham, Graham, Barrans, Sharon, Jack, Andrew, Du, Ming-Qing, Calaminici, Maria, Lister, T. Andrew, Auer, Rebecca, Montoto, Silvia, Gribben, John G., Siebert, Reiner, Chelala, Claude, Zoncu, Roberto, Sabatini, David M., Fitzgibbon, Jude
Publicado no Nat Genet (2015)