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The dawn of the age of amino acid sensors for the mTORC1 pathway

The mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth that responds to a diverse set of environmental inputs, including amino acids. Over the past ten years, a number of proteins have been identified that help transmit amino acid availability to mTORC1. However,...

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Détails bibliographiques
Publié dans:Cell Metab
Auteurs principaux: Wolfson, Rachel L., Sabatini, David M.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560103/
https://ncbi.nlm.nih.gov/pubmed/28768171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.07.001
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