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The dawn of the age of amino acid sensors for the mTORC1 pathway

The mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth that responds to a diverse set of environmental inputs, including amino acids. Over the past ten years, a number of proteins have been identified that help transmit amino acid availability to mTORC1. However,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Metab
Prif Awduron: Wolfson, Rachel L., Sabatini, David M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560103/
https://ncbi.nlm.nih.gov/pubmed/28768171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2017.07.001
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