Linear Ubiquitin Chains: Cellular Functions and Strategies for Detection and Quantification

por Dittmar, Gunnar, Winklhofer, Konstanze F.
Publicado en Front Chem (2020)

The two faces of protein misfolding: gain- and loss-of-function in neurodegenerative diseases

por Winklhofer, Konstanze F, Tatzelt, Jörg, Haass, Christian
Publicado 2008

Conserved Stress-protective Activity between Prion Protein and Shadoo

por Sakthivelu, Vignesh, Seidel, Ralf P., Winklhofer, Konstanze F., Tatzelt, Jörg
Publicado 2011

Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

por Exner, Nicole, Lutz, Anne Kathrin, Haass, Christian, Winklhofer, Konstanze F
Publicado 2012

Structural Instability of the Prion Protein upon M205S/R Mutations Revealed by Molecular Dynamics Simulations

por Hirschberger, Thomas, Stork, Martina, Schropp, Bernhard, Winklhofer, Konstanze F., Tatzelt, Jörg, Tavan, Paul
Publicado 2006

Stress-protective signalling of prion protein is corrupted by scrapie prions

por Rambold, Angelika S, Müller, Veronika, Ron, Uri, Ben-Tal, Nir, Winklhofer, Konstanze F, Tatzelt, Jörg
Publicado 2008

SecY-mediated quality control prevents the translocation of non-gated porins

por Jung, Sebastian, Bader, Verian, Natriashvili, Ana, Koch, Hans-Georg, Winklhofer, Konstanze F., Tatzelt, Jörg
Publicado en Sci Rep (2020)

Hypochlorous acid-modified human serum albumin suppresses MHC class II - dependent antigen presentation in pro-inflammatory macrophages

por Ulfig, Agnes, Bader, Verian, Varatnitskaya, Marharyta, Lupilov, Natalie, Winklhofer, Konstanze F., Leichert, Lars I.
Publicado en Redox Biol (2021)

Association of Bcl-2 with Misfolded Prion Protein Is Linked to the Toxic Potential of Cytosolic PrP

por Rambold, Angelika S., Miesbauer, Margit, Rapaport, Doron, Bartke, Till, Baier, Michael, Winklhofer, Konstanze F., Tatzelt, Jörg
Publicado 2006

α-Helical Domains Promote Translocation of Intrinsically Disordered Polypeptides into the Endoplasmic Reticulum

por Miesbauer, Margit, Pfeiffer, Natalie V., Rambold, Angelika S., Müller, Veronika, Kiachopoulos, Sophia, Winklhofer, Konstanze F., Tatzelt, Jörg
Publicado 2009

Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion

por Rolland, Stéphane G., Motori, Elisa, Memar, Nadin, Hench, Jürgen, Frank, Stephan, Winklhofer, Konstanze F., Conradt, Barbara
Publicado 2013

Activation leads to a significant shift in the intracellular redox homeostasis of neutrophil-like cells

por Xie, Kaibo, Varatnitskaya, Marharyta, Maghnouj, Abdelouahid, Bader, Verian, Winklhofer, Konstanze F., Hahn, Stephan, Leichert, Lars I.
Publicado en Redox Biol (2019)

The key role of solvent in condensation: Mapping water in liquid-liquid phase-separated FUS

por Ahlers, Jonas, Adams, Ellen M., Bader, Verian, Pezzotti, Simone, Winklhofer, Konstanze F., Tatzelt, Jörg, Havenith, Martina
Publicado en Biophys J (2021)

The N-terminal domain of the prion protein is required and sufficient for liquid–liquid phase separation: A crucial role of the Aβ-binding domain

por Kamps, Janine, Lin, Yu-Hsuan, Oliva, Rosario, Bader, Verian, Winter, Roland, Winklhofer, Konstanze F., Tatzelt, Jörg
Publicado en J Biol Chem (2021)

Cofactor Tpr2 combines two TPR domains and a J domain to regulate the Hsp70/Hsp90 chaperone system

por Brychzy, Alexander, Rein, Theo, Winklhofer, Konstanze F., Hartl, F.Ulrich, Young, Jason C., Obermann, Wolfgang M.J.
Publicado 2003

Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants

por Klein, Pontus, Müller-Rischart, Anne Kathrin, Motori, Elisa, Schönbauer, Cornelia, Schnorrer, Frank, Winklhofer, Konstanze F, Klein, Rüdiger
Publicado 2014

Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants

por Klein, Pontus, Müller-Rischart, Anne Kathrin, Motori, Elisa, Schönbauer, Cornelia, Schnorrer, Frank, Winklhofer, Konstanze F, Klein, Rüdiger
Publicado 2014

Parkin Is Protective against Proteotoxic Stress in a Transgenic Zebrafish Model

por Fett, Mareike E., Pilsl, Anna, Paquet, Dominik, van Bebber, Frauke, Haass, Christian, Tatzelt, Jörg, Schmid, Bettina, Winklhofer, Konstanze F.
Publicado 2010

A new perspective on membrane-embedded Bax oligomers using DEER and bioresistant orthogonal spin labels

por Teucher, Markus, Zhang, Hui, Bader, Verian, Winklhofer, Konstanze F., García-Sáez, Ana J., Rajca, Andrzej, Bleicken, Stephanie, Bordignon, Enrica
Publicado en Sci Rep (2019)

The Heat Shock Response Is Modulated by and Interferes with Toxic Effects of Scrapie Prion Protein and Amyloid β

por Resenberger, Ulrike K., Müller, Veronika, Munter, Lisa M., Baier, Michael, Multhaup, Gerd, Wilson, Mark R., Winklhofer, Konstanze F., Tatzelt, Jörg
Publicado 2012