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Impaired complex IV activity in response to loss of LRPPRC function can be compensated by mitochondrial hyperfusion
Mitochondrial morphology changes in response to various stimuli but the significance of this is unclear. In a screen for mutants with abnormal mitochondrial morphology, we identified MMA-1, the Caenorhabditis elegans homolog of the French Canadian Leigh Syndrome protein LRPPRC (leucine-rich pentatri...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3740885/ https://ncbi.nlm.nih.gov/pubmed/23878239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1303872110 |
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