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The loss of LRPPRC function induces the mitochondrial unfolded protein response

The inactivation of the LRPPRC gene, which has previously been associated with the neurodegenerative French Canadian Leigh Syndrome, results in a decrease in the production of mitochondria-encoded subunits of complex IV, thereby causing a reduction in complex IV activity. Previously we have shown th...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Köhler, Fabian, Müller-Rischart, Anne Kathrin, Conradt, Barbara, Rolland, Stéphane Guy
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600627/
https://ncbi.nlm.nih.gov/pubmed/26412102
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