The loss of LRPPRC function induces the mitochondrial unfolded protein response

The inactivation of the LRPPRC gene, which has previously been associated with the neurodegenerative French Canadian Leigh Syndrome, results in a decrease in the production of mitochondria-encoded subunits of complex IV, thereby causing a reduction in complex IV activity. Previously we have shown th...

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Bibliographic Details
Published in:Aging (Albany NY)
Main Authors: Köhler, Fabian, Müller-Rischart, Anne Kathrin, Conradt, Barbara, Rolland, Stéphane Guy
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4600627/
https://ncbi.nlm.nih.gov/pubmed/26412102
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