Ret rescues mitochondrial morphology and muscle degeneration of Drosophila Pink1 mutants

Parkinson's disease (PD)-associated Pink1 and Parkin proteins are believed to function in a common pathway controlling mitochondrial clearance and trafficking. Glial cell line-derived neurotrophic factor (GDNF) and its signaling receptor Ret are neuroprotective in toxin-based animal models of P...

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Bibliografske podrobnosti
Main Authors: Klein, Pontus, Müller-Rischart, Anne Kathrin, Motori, Elisa, Schönbauer, Cornelia, Schnorrer, Frank, Winklhofer, Konstanze F, Klein, Rüdiger
Format: Artigo
Jezik:Inglês
Izdano: BlackWell Publishing Ltd 2014
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983680/
https://ncbi.nlm.nih.gov/pubmed/24473149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201284290
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