Carregant...

Stress-protective signalling of prion protein is corrupted by scrapie prions

Studies in transgenic mice revealed that neurodegeneration induced by scrapie prion (PrP(Sc)) propagation is dependent on neuronal expression of the cellular prion protein PrP(C). On the other hand, there is evidence that PrP(C) itself has a stress-protective activity. Here, we show that the toxic a...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Rambold, Angelika S, Müller, Veronika, Ron, Uri, Ben-Tal, Nir, Winklhofer, Konstanze F, Tatzelt, Jörg
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2486277/
https://ncbi.nlm.nih.gov/pubmed/18566584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.122
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!