טוען...
Stress-protective signalling of prion protein is corrupted by scrapie prions
Studies in transgenic mice revealed that neurodegeneration induced by scrapie prion (PrP(Sc)) propagation is dependent on neuronal expression of the cellular prion protein PrP(C). On the other hand, there is evidence that PrP(C) itself has a stress-protective activity. Here, we show that the toxic a...
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| Main Authors: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2008
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2486277/ https://ncbi.nlm.nih.gov/pubmed/18566584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.122 |
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