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SecY-mediated quality control prevents the translocation of non-gated porins

OmpC and OmpF are among the most abundant outer membrane proteins in E. coli and serve as hydrophilic channels to mediate uptake of small molecules including antibiotics. Influx selectivity is controlled by the so-called constriction zone or eyelet of the channel. Mutations in the loop domain formin...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Jung, Sebastian, Bader, Verian, Natriashvili, Ana, Koch, Hans-Georg, Winklhofer, Konstanze F., Tatzelt, Jörg
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530735/
https://ncbi.nlm.nih.gov/pubmed/33004891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73185-y
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