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SecY-mediated quality control prevents the translocation of non-gated porins

OmpC and OmpF are among the most abundant outer membrane proteins in E. coli and serve as hydrophilic channels to mediate uptake of small molecules including antibiotics. Influx selectivity is controlled by the so-called constriction zone or eyelet of the channel. Mutations in the loop domain formin...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Jung, Sebastian, Bader, Verian, Natriashvili, Ana, Koch, Hans-Georg, Winklhofer, Konstanze F., Tatzelt, Jörg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7530735/
https://ncbi.nlm.nih.gov/pubmed/33004891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73185-y
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