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Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY
During their biosynthesis, many proteins pass through the membrane via a hydrophilic channel formed by the heterotrimeric Sec61/SecY complex. Whether this channel forms at the interface of multiple copies of Sec61/SecY or is intrinsic to a monomeric complex, as suggested by the recently solved X-ray...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2171872/ https://ncbi.nlm.nih.gov/pubmed/15851514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412019 |
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