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Disulfide bridge formation between SecY and a translocating polypeptide localizes the translocation pore to the center of SecY

During their biosynthesis, many proteins pass through the membrane via a hydrophilic channel formed by the heterotrimeric Sec61/SecY complex. Whether this channel forms at the interface of multiple copies of Sec61/SecY or is intrinsic to a monomeric complex, as suggested by the recently solved X-ray...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Cannon, Kurt S., Or, Eran, Clemons, William M., Shibata, Yoko, Rapoport, Tom A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: The Rockefeller University Press 2005
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171872/
https://ncbi.nlm.nih.gov/pubmed/15851514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200412019
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