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Protease protection assays show polypeptide movement into the SecY channel by power strokes of the SecA ATPase

Bacterial secretory proteins are translocated post‐translationally by the SecA ATPase through the protein‐conducting SecY channel in the plasma membrane. During the ATP hydrolysis cycle, SecA undergoes large conformational changes of its two‐helix finger and clamp domains, but how these changes resu...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Catipovic, Marco A, Rapoport, Tom A
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645225/
https://ncbi.nlm.nih.gov/pubmed/32969592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050905
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