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Protease protection assays show polypeptide movement into the SecY channel by power strokes of the SecA ATPase

Bacterial secretory proteins are translocated post‐translationally by the SecA ATPase through the protein‐conducting SecY channel in the plasma membrane. During the ATP hydrolysis cycle, SecA undergoes large conformational changes of its two‐helix finger and clamp domains, but how these changes resu...

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Publicado en:EMBO Rep
Autores principales: Catipovic, Marco A, Rapoport, Tom A
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7645225/
https://ncbi.nlm.nih.gov/pubmed/32969592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050905
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