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Structure of the SecY channel during initiation of protein translocation
Many secretory proteins are targeted by signal sequences to a protein-conducting channel, formed by prokaryotic SecY- or eukaryotic Sec61-complexes, and are translocated across the membrane during their synthesis(1,2). Crystal structures of the inactive channel show that the SecY subunit of the hete...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3948209/ https://ncbi.nlm.nih.gov/pubmed/24153188 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12720 |
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