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Crystal structure of a substrate-engaged SecY protein-translocation channel
Hydrophobic signal sequences target secretory polypeptides to a protein-conducting channel formed by a heterotrimeric membrane protein complex, the prokaryotic SecY or eukaryotic Sec61 complex. How signal sequences are recognized is poorly understood, particularly because they are diverse in sequenc...
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| Yayımlandı: | Nature |
|---|---|
| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4855518/ https://ncbi.nlm.nih.gov/pubmed/26950603 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature17163 |
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