HIV broadly neutralizing antibody targets

Bằng Wibmer, Constantinos Kurt, Moore, Penny L., Morris, Lynn
Xuất bản năm Curr Opin HIV AIDS (2015)

Neutralization Breadth and Potency of Single-Chain Variable Fragments Derived from Broadly Neutralizing Antibodies Targeting Multiple Epitopes on the HIV-1 Envelope

Bằng van Dorsten, Rebecca T., Lambson, Bronwen E., Wibmer, Constantinos Kurt, Weinberg, Marc S., Moore, Penny L., Morris, Lynn
Xuất bản năm J Virol (2020)

Common helical V1V2 conformations of HIV-1 Envelope expose the α4β7 binding site on intact virions

Bằng Wibmer, Constantinos Kurt, Richardson, Simone I., Yolitz, Jason, Cicala, Claudia, Arthos, James, Moore, Penny L., Morris, Lynn
Xuất bản năm Nat Commun (2018)

Viral Escape from HIV-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth through Sequential Recognition of Multiple Epitopes and Immunotypes

Bằng Wibmer, Constantinos Kurt, Bhiman, Jinal N., Gray, Elin S., Tumba, Nancy, Abdool Karim, Salim S., Williamson, Carolyn, Morris, Lynn, Moore, Penny L.
Được phát hành 2013

UCLA1, a Synthetic Derivative of a gp120 RNA Aptamer, Inhibits Entry of Human Immunodeficiency Virus Type 1 Subtype C

Bằng Mufhandu, Hazel T., Gray, Elin S., Madiga, Maphuti C., Tumba, Nancy, Alexandre, Kabamba B., Khoza, Thandeka, Wibmer, Constantinos Kurt, Moore, Penny L., Morris, Lynn, Khati, Makobetsa
Được phát hành 2012

The Neutralization Breadth of HIV-1 Develops Incrementally over Four Years and Is Associated with CD4(+) T Cell Decline and High Viral Load during Acute Infection

Bằng Gray, Elin S., Madiga, Maphuti C., Hermanus, Tandile, Moore, Penny L., Wibmer, Constantinos Kurt, Tumba, Nancy L., Werner, Lise, Mlisana, Koleka, Sibeko, Sengeziwe, Williamson, Carolyn, Abdool Karim, Salim S., Morris, Lynn
Được phát hành 2011

Genome Sequencing of a Severe Acute Respiratory Syndrome Coronavirus 2 Isolate Obtained from a South African Patient with Coronavirus Disease 2019

Bằng Allam, Mushal, Ismail, Arshad, Khumalo, Zamantungwa T. H., Kwenda, Stanford, van Heusden, Peter, Cloete, Ruben, Wibmer, Constantinos Kurt, Mtshali, Phillip Senzo, Mnyameni, Florah, Mohale, Thabo, Subramoney, Kathleen, Walaza, Sibongile, Ngubane, Wendy, Govender, Nevashan, Motaze, Nkengafac V., Bhiman, Jinal N.
Xuất bản năm Microbiol Resour Announc (2020)

South African HIV-1 subtype C transmitted variants with a specific V2 motif show higher dependence on α4β7 for replication

Bằng Richardson, Simone I, Gray, Elin S, Mkhize, Nonhlanhla N, Sheward, Daniel J, Lambson, Bronwen E, Wibmer, Constantinos Kurt, Masson, Lindi, Werner, Lise, Garrett, Nigel, Passmore, Jo-Ann S, Karim, Quarraisha Abdool, Karim, Salim S Abdool, Williamson, Carolyn, Moore, Penny L, Morris, Lynn
Xuất bản năm Retrovirology (2015)

Isolation of a Monoclonal Antibody That Targets the Alpha-2 Helix of gp120 and Represents the Initial Autologous Neutralizing-Antibody Response in an HIV-1 Subtype C-Infected Indiv...

Bằng Gray, Elin S., Moody, M. Anthony, Wibmer, Constantinos Kurt, Chen, Xi, Marshall, Dawn, Amos, Joshua, Moore, Penny L., Foulger, Andrew, Yu, Jae-Sung, Lambson, Bronwen, Abdool Karim, Salim, Whitesides, John, Tomaras, Georgia D., Haynes, Barton F., Morris, Lynn, Liao, Hua-Xin
Được phát hành 2011

Structure of an N276-Dependent HIV-1 Neutralizing Antibody Targeting a Rare V5 Glycan Hole Adjacent to the CD4 Binding Site

Bằng Wibmer, Constantinos Kurt, Gorman, Jason, Anthony, Colin S., Mkhize, Nonhlanhla N., Druz, Aliaksandr, York, Talita, Schmidt, Stephen D., Labuschagne, Phillip, Louder, Mark K., Bailer, Robert T., Abdool Karim, Salim S., Mascola, John R., Williamson, Carolyn, Moore, Penny L., Kwong, Peter D., Morris, Lynn
Xuất bản năm J Virol (2016)

Rapid Induction of Multifunctional Antibodies in Rabbits and Macaques by Clade C HIV-1 CAP257 Envelopes Circulating During Epitope-Specific Neutralization Breadth Development

Bằng Malherbe, Delphine C., Wibmer, Constantinos Kurt, Nonyane, Molati, Reed, Jason, Sather, D. Noah, Spencer, David A., Schuman, Jason T., Guo, Biwei, Pandey, Shilpi, Robins, Harlan, Park, Byung, Fuller, Deborah H., Sacha, Jonah B., Moore, Penny L., Hessell, Ann J., Haigwood, Nancy L.
Xuất bản năm Front Immunol (2020)

Antibody Specificities Associated with Neutralization Breadth in Plasma from Human Immunodeficiency Virus Type 1 Subtype C-Infected Blood Donors

Bằng Gray, Elin S., Taylor, Natasha, Wycuff, Diane, Moore, Penny L., Tomaras, Georgia D., Wibmer, Constantinos Kurt, Puren, Adrian, DeCamp, Allan, Gilbert, Peter B., Wood, Blake, Montefiori, David C., Binley, James M., Shaw, George M., Haynes, Barton F., Mascola, John R., Morris, Lynn
Được phát hành 2009

The V2 loop of HIV gp120 delivers costimulatory signals to CD4(+) T cells through Integrin α(4)β(7) and promotes cellular activation and infection

Bằng Goes, Livia R., Sajani, Alia, Sivro, Aida, Olowojesiku, Ronke, Ray, Jocelyn C., Perrone, Ian, Yolitz, Jason, Girard, Alexandre, Leyre, Louise, Wibmer, Constantinos Kurt, Morris, Lynn, Gorini, Giacomo, Franchini, Genoveffa, Mason, Rosemarie D., Roederer, Mario, Mehandru, Saurabh, Soares, Marcelo A., Cicala, Claudia, Fauci, Anthony S., Arthos, James
Xuất bản năm Proc Natl Acad Sci U S A (2020)

SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

Bằng Wibmer, Constantinos Kurt, Ayres, Frances, Hermanus, Tandile, Madzivhandila, Mashudu, Kgagudi, Prudence, Oosthuysen, Brent, Lambson, Bronwen E., de Oliveira, Tulio, Vermeulen, Marion, van der Berg, Karin, Rossouw, Theresa, Boswell, Michael, Ueckermann, Veronica, Meiring, Susan, von Gottberg, Anne, Cohen, Cheryl, Morris, Lynn, Bhiman, Jinal N., Moore, Penny L.
Xuất bản năm bioRxiv (2021)

Identification of broadly neutralizing antibody epitopes in the HIV-1 envelope glycoprotein using evolutionary models

Bằng Lacerda, Miguel, Moore, Penny L, Ngandu, Nobubelo K, Seaman, Michael, Gray, Elin S, Murrell, Ben, Krishnamoorthy, Mohan, Nonyane, Molati, Madiga, Maphuti, Wibmer, Constantinos Kurt, Sheward, Daniel, Bailer, Robert T, Gao, Hongmei, Greene, Kelli M, Karim, Salim S Abdool, Mascola, John R, Korber, Bette TM, Montefiori, David C, Morris, Lynn, Williamson, Carolyn, Seoighe, Cathal
Xuất bản năm Virol J (2013)

HIVR4P 2016, Partnering for Prevention: Conference Summary and Highlights

Bằng Shacklett, Barbara L., Derdeyn, Cynthia A., Folayan, Morenike Oluwatoyin, Landovitz, Raphael J., Anthony, Colin, Behrens, Anna-Janina, Hope, Thomas J., Landais, Elise, Leal, Lorna, Marrazzo, Jeanne M., Morris, Lynn, Mugo, Nelly, Ngure, Kenneth, Noseda, Veronica, Ranasinghe, Srinika, Tully, Damien C., Voronin, Yegor, Warren, Mitchell, Wibmer, Constantinos Kurt, Xie, Irene Y., Scarlatti, Gabriella, Thyagarajan, Bargavi
Xuất bản năm AIDS Res Hum Retroviruses (2017)

Polyclonal B Cell Responses to Conserved Neutralization Epitopes in a Subset of HIV-1-Infected Individuals

Bằng Tomaras, Georgia D., Binley, James M., Gray, Elin S., Crooks, Emma T., Osawa, Keiko, Moore, Penny L., Tumba, Nancy, Tong, Tommy, Shen, Xiaoying, Yates, Nicole L., Decker, Julie, Wibmer, Constantinos Kurt, Gao, Feng, Alam, S. Munir, Easterbrook, Philippa, Abdool Karim, Salim, Kamanga, Gift, Crump, John A., Cohen, Myron, Shaw, George M., Mascola, John R., Haynes, Barton F., Montefiori, David C., Morris, Lynn
Được phát hành 2011

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape

Bằng Wibmer, Constantinos Kurt, Gorman, Jason, Ozorowski, Gabriel, Bhiman, Jinal N., Sheward, Daniel J., Elliott, Debra H., Rouelle, Julie, Smira, Ashley, Joyce, M. Gordon, Ndabambi, Nonkululeko, Druz, Aliaksandr, Asokan, Mangai, Burton, Dennis R., Connors, Mark, Abdool Karim, Salim S., Mascola, John R., Robinson, James E., Ward, Andrew B., Williamson, Carolyn, Kwong, Peter D., Morris, Lynn, Moore, Penny L.
Xuất bản năm PLoS Pathog (2017)

SARS-CoV-2 501Y.V2 (B.1.351) elicits cross-reactive neutralizing antibodies

Bằng Moyo-Gwete, Thandeka, Madzivhandila, Mashudu, Makhado, Zanele, Ayres, Frances, Mhlanga, Donald, Oosthuysen, Brent, Lambson, Bronwen E., Kgagudi, Prudence, Tegally, Houriiyah, Iranzadeh, Arash, Doolabh, Deelan, Tyers, Lynn, Chinhoyi, Lionel R., Mennen, Mathilda, Skelem, Sango, Marais, Gert, Wibmer, Constantinos Kurt, Bhiman, Jinal N, Ueckermann, Veronica, Rossouw, Theresa, Boswell, Michael, de Oliveira, Tulio, Williamson, Carolyn, Burgers, Wendy A, Ntusi, Ntobeko, Morris, Lynn, Moore, Penny L
Xuất bản năm bioRxiv (2021)

Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α(4)β(7)

Bằng Lertjuthaporn, Sakaorat, Cicala, Claudia, Van Ryk, Donald, Liu, Matthew, Yolitz, Jason, Wei, Danlan, Nawaz, Fatima, Doyle, Allison, Horowitch, Brooke, Park, Chung, Lu, Shan, Lou, Yang, Wang, Shixia, Pan, Ruimin, Jiang, Xunqing, Villinger, Francois, Byrareddy, Siddappa N., Santangelo, Philip J., Morris, Lynn, Wibmer, Constantinos Kurt, Biris, Kristin, Mason, Rosemarie D., Gorman, Jason, Hiatt, Joseph, Martinelli, Elena, Roederer, Mario, Fujikawa, Dai, Gorini, Giacomo, Franchini, Genoveffa, Arakelyan, Anush, Ansari, Aftab A., Pattanapanyasat, Kovit, Kong, Xiang-Peng, Fauci, Anthony S., Arthos, James
Xuất bản năm PLoS Pathog (2018)