Identification of broadly neutralizing antibody epitopes in the HIV-1 envelope glycoprotein using evolutionary models

BACKGROUND: Identification of the epitopes targeted by antibodies that can neutralize diverse HIV-1 strains can provide important clues for the design of a preventative vaccine. METHODS: We have developed a computational approach that can identify key amino acids within the HIV-1 envelope glycoprote...

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Detaylı Bibliyografya
Yayımlandı:Virol J
Asıl Yazarlar: Lacerda, Miguel, Moore, Penny L, Ngandu, Nobubelo K, Seaman, Michael, Gray, Elin S, Murrell, Ben, Krishnamoorthy, Mohan, Nonyane, Molati, Madiga, Maphuti, Wibmer, Constantinos Kurt, Sheward, Daniel, Bailer, Robert T, Gao, Hongmei, Greene, Kelli M, Karim, Salim S Abdool, Mascola, John R, Korber, Bette TM, Montefiori, David C, Morris, Lynn, Williamson, Carolyn, Seoighe, Cathal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4220805/
https://ncbi.nlm.nih.gov/pubmed/24295501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-10-347
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