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Extensive purifying selection acting on synonymous sites in HIV-1 Group M sequences

<p>Abstract</p> <p>Background</p> <p>Positive selection pressure acting on protein-coding sequences is usually inferred when the rate of nonsynonymous substitution is greater than the synonymous rate. However, purifying selection acting directly on the nucleotide sequen...

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Detalhes bibliográficos
Main Authors: Martin Darren, Woodman Zenda, Moore Penny, Scheffler Konrad, Ngandu Nobubelo K, Seoighe Cathal
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2008-12-01
Colecção:Virology Journal
Acesso em linha:http://www.virologyj.com/content/5/1/160
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