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Frequent toggling between alternative amino acids is driven by selection in HIV-1.
Host immune responses against infectious pathogens exert strong selective pressures favouring the emergence of escape mutations that prevent immune recognition. Escape mutations within or flanking functionally conserved epitopes can occur at a significant cost to the pathogen in terms of its ability...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science (PLoS)
2008-12-01
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| Colecção: | PLoS Pathogens |
| Acesso em linha: | http://europepmc.org/articles/PMC2592544?pdf=render |
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