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Extensive purifying selection acting on synonymous sites in HIV-1 Group M sequences
BACKGROUND: Positive selection pressure acting on protein-coding sequences is usually inferred when the rate of nonsynonymous substitution is greater than the synonymous rate. However, purifying selection acting directly on the nucleotide sequence can lower the synonymous substitution rate. This cou...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666660/ https://ncbi.nlm.nih.gov/pubmed/19105834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-5-160 |
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