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Detecting Positive and Purifying Selection at Synonymous Sites in Yeast and Worm
We present a new computational method to identify positive and purifying selection at synonymous sites in yeast and worm. We define synonymous substitutions that change codons from preferred to unpreferred or vice versa as nonconservative synonymous substitutions and all other substitutions as conse...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2915641/ https://ncbi.nlm.nih.gov/pubmed/20231333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msq077 |
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