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A Universal Trend of Reduced mRNA Stability near the Translation-Initiation Site in Prokaryotes and Eukaryotes

Recent studies have suggested that the thermodynamic stability of mRNA secondary structure near the start codon can regulate translation efficiency in Escherichia coli, and that translation is more efficient the less stable the secondary structure. We survey the complete genomes of 340 species for s...

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Detalhes bibliográficos
Main Authors: Gu, Wanjun, Zhou, Tong, Wilke, Claus O.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2816680/
https://ncbi.nlm.nih.gov/pubmed/20140241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000664
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