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A universal strategy for regulating mRNA translation in prokaryotic and eukaryotic cells

We describe a simple strategy to control mRNA translation in both prokaryotic and eukaryotic cells which relies on a unique protein–RNA interaction. Specifically, we used the Pumilio/FBF (PUF) protein to repress translation by binding in between the ribosome binding site (RBS) and the start codon (i...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Cao, Jicong, Arha, Manish, Sudrik, Chaitanya, Mukherjee, Abhirup, Wu, Xia, Kane, Ravi S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4417184/
https://ncbi.nlm.nih.gov/pubmed/25845589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv290
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