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Detecting Amino Acid Sites Under Positive Selection and Purifying Selection
An excess of nonsynonymous over synonymous substitution at individual amino acid sites is an important indicator that positive selection has affected the evolution of a protein between the extant sequences under study and their most recent common ancestor. Several methods exist to detect the presenc...
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Genetics Society of America
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1449526/ https://ncbi.nlm.nih.gov/pubmed/15654091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.032144 |
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