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Detecting Amino Acid Sites Under Positive Selection and Purifying Selection

An excess of nonsynonymous over synonymous substitution at individual amino acid sites is an important indicator that positive selection has affected the evolution of a protein between the extant sequences under study and their most recent common ancestor. Several methods exist to detect the presenc...

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Hlavní autoři: Massingham, Tim, Goldman, Nick
Médium: Artigo
Jazyk:Inglês
Vydáno: Genetics Society of America 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1449526/
https://ncbi.nlm.nih.gov/pubmed/15654091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.104.032144
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