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Widespread Positive Selection in Synonymous Sites of Mammalian Genes

Evolution of protein sequences is largely governed by purifying selection, with a small fraction of proteins evolving under positive selection. The evolution at synonymous positions in protein-coding genes is not nearly as well understood, with the extent and types of selection remaining, largely, u...

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Detalhes bibliográficos
Main Authors: Resch, Alissa M., Carmel, Liran, Mariño-Ramírez, Leonardo, Ogurtsov, Aleksey Y., Shabalina, Svetlana A., Rogozin, Igor B., Koonin, Eugene V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2632937/
https://ncbi.nlm.nih.gov/pubmed/17522087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msm100
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