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Distinct Patterns of Expression and Evolution of Intronless and Intron-Containing Mammalian Genes

Comparison of expression levels and breadth and evolutionary rates of intronless and intron-containing mammalian genes shows that intronless genes are expressed at lower levels, tend to be tissue specific, and evolve significantly faster than spliced genes. By contrast, monomorphic spliced genes tha...

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Detalhes bibliográficos
Main Authors: Shabalina, Svetlana A., Ogurtsov, Aleksey Y., Spiridonov, Alexey N., Novichkov, Pavel S., Spiridonov, Nikolay A., Koonin, Eugene V.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908711/
https://ncbi.nlm.nih.gov/pubmed/20360214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/molbev/msq086
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