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Patterns in interspecies similarity correlate with nucleotide composition in mammalian 3′UTRs

Post-transcriptional regulation and the formation of mRNA 3′ ends are crucial for gene expression in eukaryotes. Interspecies conservation of many sequences within 3′UTRs reveals selective constraint due to similar function. To study the pattern of conservation within 3′UTRs, we compiled and aligned...

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Detalhes bibliográficos
Main Authors: Shabalina, Svetlana A., Ogurtsov, Aleksey Y., Lipman, David J., Kondrashov, Alexey S.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC203331/
https://ncbi.nlm.nih.gov/pubmed/12954780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg751
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