Potent and Broad Neutralization of HIV-1 Subtype C by Plasma Antibodies Targeting a Quaternary Epitope Including Residues in the V2 Loop

The targets of broadly cross-neutralizing (BCN) antibodies are of great interest in the HIV vaccine field. We have identified a subtype C HIV-1-superinfected individual, CAP256, with high-level BCN activity, and characterized the antibody specificity mediating breadth. CAP256 developed potent BCN ac...

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Bibliografiset tiedot
Päätekijät: Moore, Penny L., Gray, Elin S., Sheward, Daniel, Madiga, Maphuti, Ranchobe, Nthabeleng, Lai, Zhong, Honnen, William J., Nonyane, Molati, Tumba, Nancy, Hermanus, Tandile, Sibeko, Sengeziwe, Mlisana, Koleka, Abdool Karim, Salim S., Williamson, Carolyn, Pinter, Abraham, Morris, Lynn
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2011
Aiheet:
Pathogenesis and Immunity
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067856/
https://ncbi.nlm.nih.gov/pubmed/21270156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02658-10
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