Viral Escape from HIV-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth through Sequential Recognition of Multiple Epitopes and Immunotypes

Identifying the targets of broadly neutralizing antibodies to HIV-1 and understanding how these antibodies develop remain important goals in the quest to rationally develop an HIV-1 vaccine. We previously identified a participant in the CAPRISA Acute Infection Cohort (CAP257) whose plasma neutralize...

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Detalhes bibliográficos
Main Authors: Wibmer, Constantinos Kurt, Bhiman, Jinal N., Gray, Elin S., Tumba, Nancy, Abdool Karim, Salim S., Williamson, Carolyn, Morris, Lynn, Moore, Penny L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814426/
https://ncbi.nlm.nih.gov/pubmed/24204277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003738
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