Broadly Neutralizing Antibodies as Treatment: Effects on Virus and Immune System

Por Bhiman, Jinal N., Lynch, Rebecca M.
Publicado no Curr HIV/AIDS Rep (2017)

Strategies for a multi-stage neutralizing antibody-based HIV vaccine

Por Andrabi, Raiees, Bhiman, Jinal N., Burton, Dennis R.
Publicado no Curr Opin Immunol (2018)

Somatic hypermutation to counter a globally rare viral immunotype drove off-track antibodies in the CAP256-VRC26 HIV-1 V2-directed bNAb lineage

Por Sacks, David, Bhiman, Jinal N., Wiehe, Kevin, Gorman, Jason, Kwong, Peter D., Morris, Lynn, Moore, Penny L.
Publicado no PLoS Pathog (2019)

Viral Escape from HIV-1 Neutralizing Antibodies Drives Increased Plasma Neutralization Breadth through Sequential Recognition of Multiple Epitopes and Immunotypes

Por Wibmer, Constantinos Kurt, Bhiman, Jinal N., Gray, Elin S., Tumba, Nancy, Abdool Karim, Salim S., Williamson, Carolyn, Morris, Lynn, Moore, Penny L.
Publicado em 2013

COVID-19 testing in Africa: lessons learnt

Por Ondoa, Pascale, Kebede, Yenew, Loembe, Marguerite Massinga, Bhiman, Jinal N, Tessema, Sofonias Kifle, Sow, Abdourahmane, Sall, Amadou Alpha, Nkengasong, John
Publicado no Lancet Microbe (2020)

HIV Superinfection Drives De Novo Antibody Responses and Not Neutralization Breadth

Por Sheward, Daniel J., Marais, Jinny, Bekker, Valerie, Murrell, Ben, Eren, Kemal, Bhiman, Jinal N., Nonyane, Molati, Garrett, Nigel, Woodman, Zenda L., Abdool Karim, Quarraisha, Abdool Karim, Salim S., Morris, Lynn, Moore, Penny L., Williamson, Carolyn
Publicado no Cell Host Microbe (2018)

Variable Dependence on Glycan Recognition within a Lineage of V1V2-directed HIV Neutralizing Antibodies

Por Doria-Rose, Nicole A., Roark, Ryan S., Moore, Penny, Ernandes, Michael J., Bhiman, Jinal N., Schramm, Chaim A., McKee, Krisha, O'Dell, Sijy, Louder, Mark, Karim, Salim S. Abdool, Shapiro, Lawrence, Morris, Lynn, Mascola, John R.
Publicado no AIDS Res Hum Retroviruses (2014)

Genome Sequencing of a Severe Acute Respiratory Syndrome Coronavirus 2 Isolate Obtained from a South African Patient with Coronavirus Disease 2019

Por Allam, Mushal, Ismail, Arshad, Khumalo, Zamantungwa T. H., Kwenda, Stanford, van Heusden, Peter, Cloete, Ruben, Wibmer, Constantinos Kurt, Mtshali, Phillip Senzo, Mnyameni, Florah, Mohale, Thabo, Subramoney, Kathleen, Walaza, Sibongile, Ngubane, Wendy, Govender, Nevashan, Motaze, Nkengafac V., Bhiman, Jinal N.
Publicado no Microbiol Resour Announc (2020)

Plant-based production of highly potent anti-HIV antibodies with engineered posttranslational modifications

Por Singh, Advaita Acarya, Pooe, Ofentse, Kwezi, Lusisizwe, Lotter-Stark, Therese, Stoychev, Stoyan H., Alexandra, Kabamba, Gerber, Isak, Bhiman, Jinal N., Vorster, Juan, Pauly, Michael, Zeitlin, Larry, Whaley, Kevin, Mach, Lukas, Steinkellner, Herta, Morris, Lynn, Tsekoa, Tsepo Lebiletsa, Chikwamba, Rachel
Publicado no Sci Rep (2020)

Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

Por Bhiman, Jinal N., Anthony, Colin, Doria-Rose, Nicole A., Karimanzira, Owen, Schramm, Chaim A., Khoza, Thandeka, Kitchin, Dale, Botha, Gordon, Gorman, Jason, Garrett, Nigel J., Abdool Karim, Salim S., Shapiro, Lawrence, Williamson, Carolyn, Kwong, Peter D., Mascola, John R., Morris, Lynn, Moore, Penny L.
Publicado no Nat Med (2015)

Sequencing HIV-neutralizing antibody exons and introns reveals detailed aspects of lineage maturation

Por Johnson, Erik L., Doria-Rose, Nicole A., Gorman, Jason, Bhiman, Jinal N., Schramm, Chaim A., Vu, Ashley Q., Law, William H., Zhang, Baoshan, Bekker, Valerie, Abdool Karim, Salim S., Ippolito, Gregory C., Morris, Lynn, Moore, Penny L., Kwong, Peter D., Mascola, John R., Georgiou, George
Publicado no Nat Commun (2018)

SARS-CoV-2 501Y.V2 escapes neutralization by South African COVID-19 donor plasma

Por Wibmer, Constantinos Kurt, Ayres, Frances, Hermanus, Tandile, Madzivhandila, Mashudu, Kgagudi, Prudence, Oosthuysen, Brent, Lambson, Bronwen E., de Oliveira, Tulio, Vermeulen, Marion, van der Berg, Karin, Rossouw, Theresa, Boswell, Michael, Ueckermann, Veronica, Meiring, Susan, von Gottberg, Anne, Cohen, Cheryl, Morris, Lynn, Bhiman, Jinal N., Moore, Penny L.
Publicado no bioRxiv (2021)

Evolution of an HIV glycan–dependent broadly neutralizing antibody epitope through immune escape

Por Moore, Penny L, Gray, Elin S, Wibmer, C Kurt, Bhiman, Jinal N, Nonyane, Molati, Sheward, Daniel J, Hermanus, Tandile, Bajimaya, Shringkhala, Tumba, Nancy L, Abrahams, Melissa-Rose, Lambson, Bronwen E, Ranchobe, Nthabeleng, Ping, Lihua, Ngandu, Nobubelo, Karim, Quarraisha Abdool, Karim, Salim S Abdool, Swanstrom, Ronald I, Seaman, Michael S, Williamson, Carolyn, Morris, Lynn
Publicado em 2012

Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization

Por Havenar-Daughton, Colin, Carnathan, Diane G., Boopathy, Archana V., Upadhyay, Amit A., Murrell, Ben, Reiss, Samantha M., Enemuo, Chiamaka A., Gebru, Etse H., Choe, Yury, Dhadvai, Pallavi, Viviano, Federico, Kaushik, Kirti, Bhiman, Jinal N., Briney, Bryan, Burton, Dennis R., Bosinger, Steven E., Schief, William R., Irvine, Darrell J., Silvestri, Guido, Crotty, Shane
Publicado no Cell Rep (2019)

Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape

Por Wibmer, Constantinos Kurt, Gorman, Jason, Ozorowski, Gabriel, Bhiman, Jinal N., Sheward, Daniel J., Elliott, Debra H., Rouelle, Julie, Smira, Ashley, Joyce, M. Gordon, Ndabambi, Nonkululeko, Druz, Aliaksandr, Asokan, Mangai, Burton, Dennis R., Connors, Mark, Abdool Karim, Salim S., Mascola, John R., Robinson, James E., Ward, Andrew B., Williamson, Carolyn, Kwong, Peter D., Morris, Lynn, Moore, Penny L.
Publicado no PLoS Pathog (2017)

Engineered immunogen binding to alum adjuvant enhances humoral immunity

Por Moyer, Tyson J., Kato, Yu, Abraham, Wuhbet, Chang, Jason Y. H., Kulp, Daniel W., Watson, Nicki, Turner, Hannah L., Menis, Sergey, Abbott, Robert K., Bhiman, Jinal N., Melo, Mariane B., Simon, Hayley A., Herrera-De la Mata, Sara, Liang, Shu, Seumois, Gregory, Agarwal, Yash, Li, Na, Burton, Dennis R., Ward, Andrew B., Schief, William R., Crotty, Shane, Irvine, Darrell J.
Publicado no Nat Med (2020)

Author Correction: A Engineered immunogen binding to alum adjuvant enhances humoral immunity

Por Moyer, Tyson J., Kato, Yu, Abraham, Wuhbet, Chang, Jason Y. H., Kulp, Daniel W., Watson, Nicki, Turner, Hannah L., Menis, Sergey, Abbott, Robert K., Bhiman, Jinal N., Melo, Mariane B., Simon, Hayley A., Herrera-De la Mata, Sara, Liang, Shu, Seumois, Gregory, Agarwal, Yash, Li, Na, Burton, Dennis R., Ward, Andrew B., Schief, William R., Crotty, Shane, Irvine, Darrell J.
Publicado no Nat Med (2020)

SARS-CoV-2 501Y.V2 (B.1.351) elicits cross-reactive neutralizing antibodies

Por Moyo-Gwete, Thandeka, Madzivhandila, Mashudu, Makhado, Zanele, Ayres, Frances, Mhlanga, Donald, Oosthuysen, Brent, Lambson, Bronwen E., Kgagudi, Prudence, Tegally, Houriiyah, Iranzadeh, Arash, Doolabh, Deelan, Tyers, Lynn, Chinhoyi, Lionel R., Mennen, Mathilda, Skelem, Sango, Marais, Gert, Wibmer, Constantinos Kurt, Bhiman, Jinal N, Ueckermann, Veronica, Rossouw, Theresa, Boswell, Michael, de Oliveira, Tulio, Williamson, Carolyn, Burgers, Wendy A, Ntusi, Ntobeko, Morris, Lynn, Moore, Penny L
Publicado no bioRxiv (2021)

V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity

Por van Eeden, Charmaine, Kurt Wibmer, Constantinos, Scheepers, Cathrine, Richardson, Simone I., Nonyane, Molati, Lambson, Bronwen, Mkhize, Nonhlanhla N., Vijayakumar, Balakrishnan, Sheng, Zizhang, Stanfield-Oakley, Sherry, Bhiman, Jinal N., Bekker, Valerie, Hermanus, Tandile, Mabvakure, Batsirai, Ismail, Arshad, Moody, M. Anthony, Wiehe, Kevin, Garrett, Nigel, Karim, Salim Abdool, Dirr, Heini, Fernandes, Manuel A., Sayed, Yasien, Shapiro, Lawrence, Ferrari, Guido, Haynes, Barton F., Moore, Penny L., Morris, Lynn
Publicado no Cell Rep (2018)

New Member of the V1V2-Directed CAP256-VRC26 Lineage That Shows Increased Breadth and Exceptional Potency

Por Doria-Rose, Nicole A., Bhiman, Jinal N., Roark, Ryan S., Schramm, Chaim A., Gorman, Jason, Chuang, Gwo-Yu, Pancera, Marie, Cale, Evan M., Ernandes, Michael J., Louder, Mark K., Asokan, Mangaiarkarasi, Bailer, Robert T., Druz, Aliaksandr, Fraschilla, Isabella R., Garrett, Nigel J., Jarosinski, Marissa, Lynch, Rebecca M., McKee, Krisha, O'Dell, Sijy, Pegu, Amarendra, Schmidt, Stephen D., Staupe, Ryan P., Sutton, Matthew S., Wang, Keyun, Wibmer, Constantinos Kurt, Haynes, Barton F., Abdool-Karim, Salim, Shapiro, Lawrence, Kwong, Peter D., Moore, Penny L., Morris, Lynn, Mascola, John R.
Publicado no J Virol (2015)