Viral variants that initiate and drive maturation of V1V2-directed HIV-1 broadly neutralizing antibodies

The elicitation of broadly neutralizing antibodies (bNAbs) is likely to be essential for a preventative HIV-1 vaccine, but this has not yet been achieved by immunization. In contrast some HIV-1-infected individuals naturally mount bNAb responses during chronic infection, suggesting that years of mat...

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Publicado no:Nat Med
Main Authors: Bhiman, Jinal N., Anthony, Colin, Doria-Rose, Nicole A., Karimanzira, Owen, Schramm, Chaim A., Khoza, Thandeka, Kitchin, Dale, Botha, Gordon, Gorman, Jason, Garrett, Nigel J., Abdool Karim, Salim S., Shapiro, Lawrence, Williamson, Carolyn, Kwong, Peter D., Mascola, John R., Morris, Lynn, Moore, Penny L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4637988/
https://ncbi.nlm.nih.gov/pubmed/26457756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3963
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