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Plant-based production of highly potent anti-HIV antibodies with engineered posttranslational modifications
Broadly neutralising antibodies (bNAbs) against human immunodeficiency virus type 1 (HIV-1), such as CAP256-VRC26 are being developed for HIV prevention and treatment. These Abs carry a unique but crucial post-translational modification (PTM), namely O-sulfated tyrosine in the heavy chain complement...
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| Pubblicato in: | Sci Rep |
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| Autori principali: | , , , , , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7148297/ https://ncbi.nlm.nih.gov/pubmed/32277089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-63052-1 |
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