Select gp120 V2 domain specific antibodies derived from HIV and SIV infection and vaccination inhibit gp120 binding to α(4)β(7)

The GI tract is preferentially targeted during acute/early HIV-1 infection. Consequent damage to the gut plays a central role in HIV pathogenesis. The basis for preferential targeting of gut tissues is not well defined. Recombinant proteins and synthetic peptides derived from HIV and SIV gp120 bind...

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Bibliografski detalji
Izdano u:PLoS Pathog
Glavni autori: Lertjuthaporn, Sakaorat, Cicala, Claudia, Van Ryk, Donald, Liu, Matthew, Yolitz, Jason, Wei, Danlan, Nawaz, Fatima, Doyle, Allison, Horowitch, Brooke, Park, Chung, Lu, Shan, Lou, Yang, Wang, Shixia, Pan, Ruimin, Jiang, Xunqing, Villinger, Francois, Byrareddy, Siddappa N., Santangelo, Philip J., Morris, Lynn, Wibmer, Constantinos Kurt, Biris, Kristin, Mason, Rosemarie D., Gorman, Jason, Hiatt, Joseph, Martinelli, Elena, Roederer, Mario, Fujikawa, Dai, Gorini, Giacomo, Franchini, Genoveffa, Arakelyan, Anush, Ansari, Aftab A., Pattanapanyasat, Kovit, Kong, Xiang-Peng, Fauci, Anthony S., Arthos, James
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2018
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6130882/
https://ncbi.nlm.nih.gov/pubmed/30153309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007278
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