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Vaccine Focusing to Cross-Subtype HIV-1 gp120 Variable Loop Epitopes
We designed synthetic, epitope-focused immunogens that preferentially display individual neutralization epitopes targeted by cross-subtype anti-HIV V3 loop neutralizing monoclonal antibodies (mAbs). Vaccination of rabbits with these immunogens resulted in the elicitation of distinct polyclonal serum...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138239/ https://ncbi.nlm.nih.gov/pubmed/25045827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.07.026 |
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