Rationally Designed Vaccines Targeting the V2 Region of HIV-1 gp120 Induce a Focused, Cross-Clade-Reactive, Biologically Functional Antibody Response

Strong antibody (Ab) responses against V1V2 epitopes of the human immunodeficiency virus type 1 (HIV-1) gp120 envelope (Env) correlated with reduced infection rates in studies of HIV, simian-human immunodeficiency virus (SHIV), and simian immunodeficiency virus (SIV). In order to focus the Ab respon...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Zolla-Pazner, Susan, Powell, Rebecca, Yahyaei, Sara, Williams, Constance, Jiang, Xunqing, Li, Wei, Lu, Shan, Wang, Shixia, Upadhyay, Chitra, Hioe, Catarina E., Totrov, Max, Kong, Xiangpeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126359/
https://ncbi.nlm.nih.gov/pubmed/27630234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01403-16
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