Cross-Clade HIV-1 Neutralizing Antibodies Induced with V3-Scaffold Protein Immunogens following Priming with gp120 DNA

The V3 epitope is a known target for HIV-1 neutralizing antibodies (NAbs), and V3-scaffold fusion proteins used as boosting immunogens after gp120 DNA priming were previously shown to induce NAbs in rabbits. Here, we evaluated whether the breadth and potency of the NAb response could be improved whe...

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Hlavní autoři: Zolla-Pazner, Susan, Kong, X.-P., Jiang, Xunqing, Cardozo, Timothy, Nádas, Arthur, Cohen, Sandra, Totrov, Maxim, Seaman, Michael S., Wang, Shixia, Lu, Shan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Vaccines and Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196418/
https://ncbi.nlm.nih.gov/pubmed/21795338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05086-11
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