Cross-Clade HIV-1 Neutralizing Antibodies Induced with V3-Scaffold Protein Immunogens following Priming with gp120 DNA

The V3 epitope is a known target for HIV-1 neutralizing antibodies (NAbs), and V3-scaffold fusion proteins used as boosting immunogens after gp120 DNA priming were previously shown to induce NAbs in rabbits. Here, we evaluated whether the breadth and potency of the NAb response could be improved whe...

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Hauptverfasser: Zolla-Pazner, Susan, Kong, X.-P., Jiang, Xunqing, Cardozo, Timothy, Nádas, Arthur, Cohen, Sandra, Totrov, Maxim, Seaman, Michael S., Wang, Shixia, Lu, Shan
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2011
Schlagworte:
Vaccines and Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3196418/
https://ncbi.nlm.nih.gov/pubmed/21795338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05086-11
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