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Infectivity and Neutralization of Simian Immunodeficiency Virus with FLAG Epitope Insertion in gp120 Variable Loops

A FLAG epitope tag was substituted within variable loop 1 (V1), 2 (V2), or 4 (V4) of the gp120 envelope glycoprotein of simian immunodeficiency virus strain 239 (SIV239) to evaluate the extent to which each variable loop may serve as a target for antibody-mediated neutralization. Two sites within ea...

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Bibliographic Details
Main Authors: Laird, Melissa E., Desrosiers, Ronald C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045528/
https://ncbi.nlm.nih.gov/pubmed/17686865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00831-07
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