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Neutralizing Capacity of Monoclonal Antibodies That Recognize Peptide Sequences Underlying the Carbohydrates on gp41 of Simian Immunodeficiency Virus

Extensive glycosylation of the envelope spikes of human and simian immunodeficiency virus (HIV and SIV) is an important factor for the resistance of these viruses to neutralization by antibodies. SIVmac239 gp41 has three closely spaced sites for N-linked carbohydrate attachment. Rhesus macaques expe...

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Detalhes bibliográficos
Main Authors: Martinez-Navio, José M., Desrosiers, Ronald C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497684/
https://ncbi.nlm.nih.gov/pubmed/22993152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01959-12
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