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Neutralizing Capacity of Monoclonal Antibodies That Recognize Peptide Sequences Underlying the Carbohydrates on gp41 of Simian Immunodeficiency Virus

Extensive glycosylation of the envelope spikes of human and simian immunodeficiency virus (HIV and SIV) is an important factor for the resistance of these viruses to neutralization by antibodies. SIVmac239 gp41 has three closely spaced sites for N-linked carbohydrate attachment. Rhesus macaques expe...

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Main Authors: Martinez-Navio, José M., Desrosiers, Ronald C.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497684/
https://ncbi.nlm.nih.gov/pubmed/22993152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01959-12
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