Vaccine Focusing to Cross-Subtype HIV-1 gp120 Variable Loop Epitopes

We designed synthetic, epitope-focused immunogens that preferentially display individual neutralization epitopes targeted by cross-subtype anti-HIV V3 loop neutralizing monoclonal antibodies (mAbs). Vaccination of rabbits with these immunogens resulted in the elicitation of distinct polyclonal serum...

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Autores principales: Cardozo, Timothy, Wang, Shixia, Jiang, Xunqing, Kong, Xiang-Peng, Hioe, Catarina, Krachmarov, Chavdar
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4138239/
https://ncbi.nlm.nih.gov/pubmed/25045827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.07.026
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