Significance testing as perverse probabilistic reasoning

Por Westover, M Brandon, Westover, Kenneth D, Bianchi, Matt T
Publicado em 2011

Structural dataset for the fast-exchanging KRAS G13D

Por Lu, Jia, Hunter, John, Manandhar, Anuj, Gurbani, Deepak, Westover, Kenneth D.
Publicado no Data Brief (2015)

Diffusion of nucleoside triphosphates and role of the entry site to the RNA polymerase II active center

Por Batada, Nizar N., Westover, Kenneth D., Bushnell, David A., Levitt, Michael, Kornberg, Roger D.
Publicado em 2004

Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis

Por Wang, Dong, Bushnell, David A., Westover, Kenneth D., Kaplan, Craig D., Kornberg, Roger D.
Publicado em 2006

Structural basis of transcription: Backtracked RNA polymerase II at 3.4 Å resolution

Por Wang, Dong, Bushnell, David A., Huang, Xuhui, Westover, Kenneth D., Levitt, Michael, Kornberg, Roger D.
Publicado em 2009

Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Por Taipale, Mikko, Krykbaeva, Irina, Koeva, Martina, Kayatekin, Can, Westover, Kenneth D., Karras, Georgios I., Lindquist, Susan
Publicado em 2012

Inhibition of Cell Proliferation in an NRAS Mutant Melanoma Cell Line by Combining Sorafenib and α-Mangostin

Por Xia, Yun, Li, Ying, Westover, Kenneth D., Sun, Jiaming, Chen, Hongxiang, Zhang, Jianming, Fisher, David E.
Publicado no PLoS One (2016)

Should a Sentinel Node Biopsy Be Performed in Patients with High-Risk Breast Cancer?

Por Westover, Kenneth D., Westover, M. Brandon, Winer, Eric P., Richardson, Andrea L., Iglehart, J. Dirk, Punglia, Rinaa S.
Publicado em 2011

Proton SBRT For Medically Inoperable Stage I NSCLC

Por Westover, Kenneth D, Seco, Joao, Adams, Judith A, Lanuti, Michael, Choi, Noah C, Engelsman, Martijn, Willers, Henning
Publicado em 2012

Structural dynamics in Ras and related proteins upon nucleotide switching

Por Harrison, Rane A., Lu, Jia, Carrasco, Martin, Hunter, John, Manandhar, Anuj, Gondi, Sudershan, Westover, Kenneth D., Engen, John R.
Publicado no J Mol Biol (2016)

Structural and Biochemical Analyses Reveal the Mechanism of Glutathione S-Transferase Pi 1 Inhibition by the Anti-cancer Compound Piperlongumine

Por Harshbarger, Wayne, Gondi, Sudershan, Ficarro, Scott B., Hunter, John, Udayakumar, Durga, Gurbani, Deepak, Singer, William D., Liu, Yan, Li, Lianbo, Marto, Jarrod A., Westover, Kenneth D.
Publicado no J Biol Chem (2017)

Covalent Guanosine Mimetic Inhibitors of G12C KRAS

Por Xiong, Yuan, Lu, Jia, Hunter, John, Li, Lianbo, Scott, David, Choi, Hwan Geun, Lim, Sang Min, Manandhar, Anuj, Gondi, Sudershan, Sim, Taebo, Westover, Kenneth D., Gray, Nathanael S.
Publicado no ACS Med Chem Lett (2016)

Torin2 Suppresses Ionizing Radiation-Induced DNA Damage Repair

Por Udayakumar, Durga, Pandita, Raj K., Horikoshi, Nobuo, Liu, Yan, Liu, Qingsong, Wong, Kwok-Kin, Hunt, Clayton R., Gray, Nathanael S., Minna, John D., Pandita, Tej K., Westover, Kenneth D.
Publicado no Radiat Res (2016)

Direct targeting of β-catenin by a small molecule stimulates proteasomal degradation and suppresses oncogenic Wnt/β-catenin signaling

Por Hwang, So-Young, Deng, Xianming, Byun, Sanguine, Lee, Chan, Lee, Seung-Joo, Suh, Hyunsuk, Zhang, Jianming, Kang, Qiaofeng, Zhang, Ting, Westover, Kenneth D., Mandinova, Anna, Lee, Sam W.
Publicado no Cell Rep (2016)

Shell feature: a new radiomics descriptor for predicting distant failure after radiotherapy in non-small cell lung cancer and cervix cancer

Por Hao, Hongxia, Zhou, Zhiguo, Li, Shulong, Maquilan, Genevieve, Folkert, Michael R., Iyengar, Puneeth, Westover, Kenneth D., Albuquerque, Kevin, Liu, Fang, Choy, Hak, Timmerman, Robert, Yang, Lin, Wang, Jing
Publicado no Phys Med Biol (2018)

In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C

Por Hunter, John C., Gurbani, Deepak, Ficarro, Scott B., Carrasco, Martin A., Lim, Sang Min, Choi, Hwan Geun, Xie, Ting, Marto, Jarrod A., Chen, Zhe, Gray, Nathanael S., Westover, Kenneth D.
Publicado em 2014

Development of small molecules targeting the pseudokinase Her3

Por Lim, Sang Min, Xie, Ting, Westover, Kenneth D., Ficarro, Scott B., Tae, Hyun Seop, Gurbani, Deepak, Sim, Taebo, Marto, Jarrod A., Jänne, Pasi A., Crews, Craig M., Gray, Nathanael S.
Publicado no Bioorg Med Chem Lett (2015)

Consolidative Radiotherapy for Limited Metastatic Non–Small-Cell Lung Cancer: A Phase 2 Randomized Clinical Trial

Por Iyengar, Puneeth, Wardak, Zabi, Gerber, David E., Tumati, Vasu, Ahn, Chul, Hughes, Randall S., Dowell, Jonathan E., Cheedella, Naga, Nedzi, Lucien, Westover, Kenneth D., Pulipparacharuvil, Suprabha, Choy, Hak, Timmerman, Robert D.
Publicado no JAMA Oncol (2017)

GADD45α sensitizes cervical cancer cells to radiotherapy via increasing cytoplasmic APE1 level

Por Li, Qing, Wei, Xi, Zhou, Zhi-Wei, Wang, Shu-Nan, Jin, Hua, Chen, Kui-Jun, Luo, Jia, Westover, Kenneth D., Wang, Jian-Min, Wang, Dong, Xu, Cheng-Xiong, Shan, Jin-Lu
Publicado no Cell Death Dis (2018)

Pharmacological Targeting of the Pseudokinase Her3

Por Xie, Ting, Lim, Sang Min, Westover, Kenneth D., Dodge, Michael E., Ercan, Dalia, Ficarro, Scott B., Udayakumar, Durga, Gurbani, Deepak, Tae, Hyun Seop, Riddle, Steven M., Sim, Taebo, Marto, Jarrod A., Jänne, Pasi A., Crews, Craig M., Gray, Nathanael S.
Publicado no Nat Chem Biol (2014)